| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPOUT1 |
| Gene ID: | 51490 |
| Uniprot ID: | CI114_HUMAN |
| Immunogen Region: | 163-340 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 163-340 of human C9orf114 (NP_057474.2). |
| Immunogen Sequence: | HQDLQFAGLLNPLDSPHHMR QDEESEFREGIVVDRPTRPG HGSFVNCGMKKEVKIDKNLE PGLRVTVRLNQQQHPDCKTY HGKVVSSQDPRTKAGLYWGY TVRLASCLSAVFAEAPFQDG YDLTIGTSERGSDVASAQLP NFRHALVVFGGLQGLEAGAD ADPNLEVAEPSVLFDLYV |
| Function | Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level. |
| Protein Name | Putative Methyltransferase C9orf114Centromere Protein 32Cenp-32Kinetochore-Associated ProteinSpout Domain-Containing Methyltransferase 1 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleChromosomeCentromereKinetochoreMicrotubule Organizing CenterCentrosomeAssociated With The Outer Kinetochore |
| Alternative Antibody Names | Anti-Putative Methyltransferase C9orf114 antibodyAnti-Centromere Protein 32 antibodyAnti-Cenp-32 antibodyAnti-Kinetochore-Associated Protein antibodyAnti-Spout Domain-Containing Methyltransferase 1 antibodyAnti-SPOUT1 antibodyAnti-C9orf114 antibody |
Information sourced from Uniprot.org