| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C2 (453-752) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C2 |
| Gene ID: |
717 |
| Uniprot ID: |
CO2_HUMAN |
| Immunogen Region: |
453-752 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 453-752 of human C2 (NP_000054.2). |
| Immunogen Sequence: |
LDVSKLTDTICGVGNMSANA SDQERTPWHVTIKPKSQETC RGALISDQWVLTAAHCFRDG NDHSLWRVNVGDPKSQWGKE FLIEKAVISPGFDVFAKKNQ GILEFYGDDIALLKLAQKVK MSTHARPICLPCTMEANLAL RRPQGSTCRDHENELLNKQS VPAHFVALNGSKLNINLKMG VEWTSCAEVVSQEKTMFPNL TDVREVVTDQFLCSGTQEDE SPCKGESGGAVFLERRFRF |
| Function | Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. |
| Protein Name | Complement C2C3/C5 Convertase Cleaved Into - Complement C2b Fragment - Complement C2a Fragment |
| Database Links | Reactome: R-HSA-166663Reactome: R-HSA-174577Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement C2 antibodyAnti-C3/C5 Convertase Cleaved Into - Complement C2b Fragment - Complement C2a Fragment antibodyAnti-C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
