• Western blot analysis of various lysates using C1R Rabbit polyclonal antibody (STJ118096) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-C1R antibody (466-705) (STJ118096)

SKU:
STJ118096

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C1R (466-705) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1R
Gene ID: 715
Uniprot ID: C1R_HUMAN
Immunogen Region: 466-705
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 466-705 of human C1R (NP_001724.3).
Immunogen Sequence: GGQKAKMGNFPWQVFTNIHG RGGGALLGDRWILTAAHTLY PKEHEAQSNASLDVFLGHTN VEELMKLGNHPIRRVSVHPD YRQDESYNFEGDIALLELEN SVTLGPNLLPICLPDNDTFY DLGLMGYVSGFGVMEEKIAH DLRFVRLPVANPQACENWLR GKNRMDVFSQNMFCAGHPSL KQDACQGDSGGVFAVRDPNT DRWVATGIVSWGIGCSRGYG FYTKVLNYVDWIKKEMEEE
Post Translational Modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Function C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Protein Name Complement C1r Subcomponent
Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain
Database Links Reactome: R-HSA-166663
Reactome: R-HSA-173623
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement C1r Subcomponent antibody
Anti-Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain antibody
Anti-C1R antibody

Information sourced from Uniprot.org

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