| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C1orf146 (100-180) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.68-0.70 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:4, 000ELISA: 1:4, 000IP: 1:150IHC: 1:50-1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SPO16 |
| Gene ID: | 388649 |
| Uniprot ID: | SPO16_HUMAN |
| Immunogen Region: | 100-180 |
| Immunogen: | Synthetic peptide taken within amino acid region 100-180 on human C1orf146 protein. |
| Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
| Protein Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
| Cellular Localisation | Chromosome |
| Alternative Antibody Names | Anti-Protein Spo16 Homolog antibodyAnti-Synaptonemal Complex Reinforcing Element antibodyAnti-SPO16 antibodyAnti-C1orf146 antibodyAnti-SCRE antibody |
Information sourced from Uniprot.org
