![Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/151911/346983/STJ16101402_1__22936.1681999222.jpg?c=1 "Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)")
![Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/151911/346983/STJ16101402_1__22936.1681999222.jpg?c=1 "Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)")
| Host: | Mouse |
| Applications: | IHC-P/ICC/IF |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-c-MET (Hepatocyte Growth Factor Receptor) for use in IHC-P, ICC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 3D4 |
| Conjugation: | Unconjugated |
| Isotype: | IG2a |
| Formulation: | PBS with 1% BSA and 0.1% sodium azide |
| Dilution Range: | IHC-PICCIF 1:250 |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Synthetic peptide derived from cytoplasmic domain of human c-Met protein |
| Background | MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. |
Information sourced from Uniprot.org
