| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BYSL |
| Gene ID: | 705 |
| Uniprot ID: | BYST_HUMAN |
| Immunogen Region: | 120-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human BYSL (NP_004044.3). |
| Immunogen Sequence: | HAEVVVDPEDERAIEMFMNK NPPARRTLADIIMEKLTEKQ TEVETVMSEVSGFPMPQLDP RVLEVYRGVREVLSKYRSGK LPKAFKIIPALSNWEQILYV TEPEAWTAAAMYQATRIFAS NLKERMAQRFYNLVLLPRVR DDVAEYKRLNFHLYMALKKA L |
| Tissue Specificity | Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. |
| Function | Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos. |
| Protein Name | Bystin |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | CytoplasmNucleusNucleolusAssociated With 40s Ribosomal Subunits |
| Alternative Antibody Names | Anti-Bystin antibodyAnti-BYSL antibodyAnti-ENP1 antibody |
Information sourced from Uniprot.org