Immunohistochemistry analysis of paraffin-embedded Human breast cancer using BTF3 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Anti-BTF3 antibody (2-105 aa) [R01-2B7] (STJA0011049)

SKU:
STJA0011049-100
$332.78
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Host: Rabbit
Applications: WB/IHC-P/IP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-BTF3 (2-105 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications.
Clonality : Monoclonal
Clone ID : R01-2B7
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/ml
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: BTF3
Gene ID: 689
Uniprot ID: BTF3_HUMAN
Immunogen Region: 2-105 aa
Immunogen: Recombinant protein of human BTF3
Function When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Protein Name Transcription Factor Btf3
Nascent Polypeptide-Associated Complex Subunit Beta
Nac-Beta
Rna Polymerase B Transcription Factor 3
Cellular Localisation Cytoplasm
Nucleus
The Heterodimer With Naca Is Cytoplasmic
Alternative Antibody Names Anti-Transcription Factor Btf3 antibody
Anti-Nascent Polypeptide-Associated Complex Subunit Beta antibody
Anti-Nac-Beta antibody
Anti-Rna Polymerase B Transcription Factor 3 antibody
Anti-BTF3 antibody
Anti-NACB antibody
Anti-OK antibody
Anti-SW-cl.8 antibody

Information sourced from Uniprot.org

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