| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BTB/POZ domain-containing protein 1 (115-165 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BTBD1 |
| Gene ID: | 53339 |
| Uniprot ID: | BTBD1_HUMAN |
| Immunogen Region: | 115-165 aa |
| Specificity: | This antibody detects endogenous levels of BTBD1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human BTBD1 at the amino acid range 115-165 |
| Function | Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis. |
| Protein Name | Btb/Poz Domain-Containing Protein 1Hepatitis C Virus Ns5a-Transactivated Protein 8Hcv Ns5a-Transactivated Protein 8 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmLocalizes To Punctate Or Elongated Cytoplasmic Bodies |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 1 antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibodyAnti-Hcv Ns5a-Transactivated Protein 8 antibodyAnti-BTBD1 antibodyAnti-C15orf1 antibodyAnti-NS5ATP8 antibody |
Information sourced from Uniprot.org