| Host: | Rabbit |
| Applications: | ELISA/CM/ICC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BST1 (255-274) is suitable for use in ELISA, Confocal Microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.68 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IHC: 1:200 ICC: 1:200 IF: 1:200 CFM: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | BST1 |
| Gene ID: | 683 |
| Uniprot ID: | BST1_HUMAN |
| Immunogen Region: | 255-274 |
| Specificity: | Does not cross react to other members of the Ras family or to other ARF members. |
| Immunogen: | Synthetic peptide corresponding to amino acids 255-274 of Human Bone marrow stromal cell antigen 1. Peptide was covalently modified. |
| Tissue Specificity | Expressed in various tissues including placenta, lung, liver and kidney. |
| Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 Adp-Ribosyl Cyclase 2 Bone Marrow Stromal Cell Antigen 1 Bst-1 Cyclic Adp-Ribose Hydrolase 2 Cadpr Hydrolase 2 Cd Antigen Cd157 |
| Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-196807 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 antibody Anti-Adp-Ribosyl Cyclase 2 antibody Anti-Bone Marrow Stromal Cell Antigen 1 antibody Anti-Bst-1 antibody Anti-Cyclic Adp-Ribose Hydrolase 2 antibody Anti-Cadpr Hydrolase 2 antibody Anti-Cd Antigen Cd157 antibody Anti-BST1 antibody |
Information sourced from Uniprot.org