| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BRINP3 |
| Gene ID: | 339479 |
| Uniprot ID: | BRNP3_HUMAN |
| Immunogen Region: | 240-500 |
| Immunogen Sequence: | LQGLQVLLPDYLQERFVQAA LSYIACNSEGEFICKENDCW CHCGPKFPECNCPSMDIQAM EENLLRITETWKAYNSDFEE SDEFKLFMKRLPMNYFLNTS TIMHLWTMDSNFQRRYEQLE NSMKQLFLKAQKIVHKLFSL SKRCHKQPLISLPRQRTSTY WLTRIQSFLYCNENGLLGSF SEETHSCTCPNDQVVCTAFL PCTVGDASACLTCAPDNRTR CGTCNTGYMLSQGLCKPEV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-500 of human BRINP3 (NP_950252.1). |
| Tissue Specificity | Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues. |
| Function | Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development. |
| Protein Name | Bmp/Retinoic Acid-Inducible Neural-Specific Protein 3Dbccr1-Like Protein 1 |
| Database Links | |
| Cellular Localisation | SecretedMitochondrion |
| Alternative Antibody Names | Anti-Bmp/Retinoic Acid-Inducible Neural-Specific Protein 3 antibodyAnti-Dbccr1-Like Protein 1 antibodyAnti-BRINP3 antibodyAnti-DBCCR1L antibodyAnti-DBCCR1L1 antibodyAnti-FAM5C antibody |
Information sourced from Uniprot.org
