• Western blot analysis of various lysates, using BRD2 antibody (STJ11105037) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-BRD2 antibody (1-345) [S5037RM] (STJ11105037)

SKU:
STJ11105037

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Bromodomain-Containing Protein 2 (1-345) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5037RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BRD2
Gene ID: 6046
Uniprot ID: BRD2_HUMAN
Immunogen Region: 1-345
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human BRD2 (NP_005095.1).
Immunogen Sequence: MLQNVTPHNKLPGEGNAGLL GLGPEAAAPGKRIRKPSLLY EGFESPTMASVPALQLTPAN PPPPEVSNPKKPGRVTNQLQ YLHKVVMKALWKHQFAWPFR QPVDAVKLGLPDYHKIIKQP MDMGTIKRRLENNYYWAASE CMQDFNTMFTNCYIYNKPTD DIVLMAQTLEKIFLQKVASM PQEEQELVVTIPKNSHKKGA KLAALQGSVTSAHQVPAVSS VSHTALYTPPPEIPTTVLN
Function May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.
Protein Name Bromodomain-Containing Protein 2
O27.1.1
Really Interesting New Gene 3 Protein
Database Links Reactome: R-HSA-8951936
Cellular Localisation Nucleus
Detected On Chromatin And Nucleosomes
Alternative Antibody Names Anti-Bromodomain-Containing Protein 2 antibody
Anti-O27.1.1 antibody
Anti-Really Interesting New Gene 3 Protein antibody
Anti-BRD2 antibody
Anti-KIAA9001 antibody
Anti-RING3 antibody

Information sourced from Uniprot.org

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