| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Brachyury (235-435aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ZR391 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | TBXT |
| Gene ID: | 6862 |
| Uniprot ID: | TBXT_HUMAN |
| Immunogen Region: | 235-435aa |
| Specificity: | Positive Control: Chordoma |
| Immunogen: | Recombinant fragment (around aa 235-435) of human TBXT protein |
| Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
| Protein Name | T-Box Transcription Factor TBrachyury ProteinProtein T |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9793380Reactome: R-HSA-9796292Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Transcription Factor T antibodyAnti-Brachyury Protein antibodyAnti-Protein T antibodyAnti-TBXT antibodyAnti-T antibody |
Information sourced from Uniprot.org
