Function | Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate. |
Protein Name | 3'(2' -5'-Bisphosphate Nucleotidase 13'-Phosphoadenosine 5'-Phosphate PhosphatasePap PhosphataseBisphosphate 3'-Nucleotidase 1Bpntase 1HspipInositol-Polyphosphate 1-Phosphatase |
Database Links | Reactome: R-HSA-156584 |
Alternative Antibody Names | Anti-3'(2' -5'-Bisphosphate Nucleotidase 1 antibodyAnti-3'-Phosphoadenosine 5'-Phosphate Phosphatase antibodyAnti-Pap Phosphatase antibodyAnti-Bisphosphate 3'-Nucleotidase 1 antibodyAnti-Bpntase 1 antibodyAnti-Hspip antibodyAnti-Inositol-Polyphosphate 1-Phosphatase antibodyAnti-BPNT1 antibody |
Information sourced from Uniprot.org