Western blot analysis of extracts of various cell lines, using BMPR2 Rabbit polyclonal antibody (STJ118671) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.

Anti-BMPR2 antibody (739-1038) (STJ118671)

SKU:
STJ118671
£112.50 - £524.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR2
Gene ID: 659
Uniprot ID: BMPR2_HUMAN
Immunogen Region: 739-1038
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 739-1038 of human BMPR2 (NP_001195.2).
Immunogen Sequence: PTQIYPLPKQQNLPKRPTSL PLNTKNSTKEPRLKFGSKHK SNLKQVETGVAKMNTINAAE PHVVTVTMNGVAGRNHSVNS HAATTQYANGTVLSGQTTNI VTHRAQEMLQNQFIGEDTRL NINSSPDEHEPLLRREQQAG HDEGVLDRLVDRRERPLEGG RTNSNNNNSNPCSEQDVLAQ GVPSTAADPGPSKPRRAQRP NSLDLSATNVLDGSSIQIGE STQDGKSGSGEKIKKRVKT
Tissue Specificity Highly expressed in heart and liver.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Protein Name Bone Morphogenetic Protein Receptor Type-2
Bmp Type-2 Receptor
Bmpr-2
Bone Morphogenetic Protein Receptor Type Ii
Bmp Type Ii Receptor
Bmpr-Ii
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-2 antibody
Anti-Bmp Type-2 Receptor antibody
Anti-Bmpr-2 antibody
Anti-Bone Morphogenetic Protein Receptor Type Ii antibody
Anti-Bmp Type Ii Receptor antibody
Anti-Bmpr-Ii antibody
Anti-BMPR2 antibody
Anti-PPH1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0010106 Anti-BMPR2 antibody (STJA0010106) Rabbit Polyclonal Human/Mouse/Rat/Monkey WB/ELISA
STJ73311 Anti-BMPR2 antibody (Internal) (STJ73311) Goat Polyclonal Human/Mouse/Rat/Dog/Cow Pep-ELISA/WB
STJ97877 Anti-BMPR2 antibody [3F6] (STJ97877) Mouse Monoclonal Human/Mouse/Rat/Monkey WB/IHC/IF/ELISA
STJ11100052 Anti-BMPR2 antibody (27-150) (STJ11100052) Rabbit Polyclonal Human WB/ELISA
STJ27633 Anti-BMPR2 antibody (27-150) (STJ27633) Rabbit Polyclonal Human/Mouse/Rat WB/IF/ICC/ELISA
STJ11105606 Anti-TNK2 antibody (939-1038) (STJ11105606) Rabbit Polyclonal Human/Mouse IF/ICC/ELISA
STJ25905 Anti-TNK2 antibody (920-1038) (STJ25905) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/ELISA
STJ119176 Anti-BMPR2 antibody (27-150) (STJ119176) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/IF/ICC/ELISA
STJ11103460 Anti-ADARB2 antibody (600-739) (STJ11103460) Rabbit Polyclonal Human WB/ELISA
!