| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCO1 |
| Gene ID: | 53630 |
| Uniprot ID: | BCDO1_HUMAN |
| Immunogen Region: | 268-547 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2). |
| Immunogen Sequence: | MSWASCLAFHREEKTYIHII DQRTRQPVQTKFYTDAMVVF HHVNAYEEDGCIVFDVIAYE DNSLYQLFYLANLNQDFKEN SRLTSVPTLRRFAVPLHVDK NAEVGTNLIKVASTTATALK EEDGQVYCQPEFLYEGLELP RVNYAHNGKQYRYVFATGVQ WSPIPTKIIKYDILTKSSLK WREDDCWPAEPLFVPAPGAK DEDDGVILSAIVSTDPQKLP FLLILDAKSFTELARASVD |
| Tissue Specificity | Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon. |
| Function | Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism. |
| Protein Name | Beta -Beta-Carotene 15 -15'-DioxygenaseBeta-Carotene Dioxygenase 1Beta-Carotene Oxygenase 1 |
| Database Links | Reactome: R-HSA-975634 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Beta -Beta-Carotene 15 -15'-Dioxygenase antibodyAnti-Beta-Carotene Dioxygenase 1 antibodyAnti-Beta-Carotene Oxygenase 1 antibodyAnti-BCO1 antibodyAnti-BCDO antibodyAnti-BCDO1 antibodyAnti-BCMO1 antibody |
Information sourced from Uniprot.org