| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-3-Methyl-2-Oxobutanoate Dehydrogenase Lipoamide Kinase-Mitochondrial (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4107RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BCKDK |
| Gene ID: |
10295 |
| Uniprot ID: |
BCKD_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BCKDK (O14874). |
| Immunogen Sequence: |
MILASVLRSGPGGGLPLRPL LGPALALRARSTSATDTHHV EMARERSKTVTSFYNQSAID AAAEKPSVRLTPTMMLYAGR SQDGSHLLKSARYLQQELPV |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. |
| Protein Name | 3-Methyl-2-Oxobutanoate Dehydrogenase Lipoamide Kinase - MitochondrialBranched-Chain Alpha-Ketoacid Dehydrogenase KinaseBckd-KinaseBckdhkin |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion |
| Alternative Antibody Names | Anti-3-Methyl-2-Oxobutanoate Dehydrogenase Lipoamide Kinase - Mitochondrial antibodyAnti-Branched-Chain Alpha-Ketoacid Dehydrogenase Kinase antibodyAnti-Bckd-Kinase antibodyAnti-Bckdhkin antibodyAnti-BCKDK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
