| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Pre-mRNA-splicing factor SPF27 (176-225 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCAS2 |
| Gene ID: | 10286 |
| Uniprot ID: | SPF27_HUMAN |
| Immunogen Region: | 176-225 aa |
| Specificity: | BCAS2 Polyclonal Antibody detects endogenous levels of BCAS2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human BCAS2 at the amino acid range 176-225 |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
| Protein Name | Pre-Mrna-Splicing Factor Spf27Breast Carcinoma-Amplified Sequence 2Dna Amplified In Mammary Carcinoma 1 ProteinSpliceosome-Associated Protein Spf 27 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Pre-Mrna-Splicing Factor Spf27 antibodyAnti-Breast Carcinoma-Amplified Sequence 2 antibodyAnti-Dna Amplified In Mammary Carcinoma 1 Protein antibodyAnti-Spliceosome-Associated Protein Spf 27 antibodyAnti-BCAS2 antibodyAnti-DAM1 antibody |
Information sourced from Uniprot.org
