| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BANK1 (516-785) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BANK1 |
| Gene ID: |
55024 |
| Uniprot ID: |
BANK1_HUMAN |
| Immunogen Region: |
516-785 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 516-785 of human BANK1 (NP_060405.4). |
| Immunogen Sequence: |
PVANAFQLERPHFTLPGTMV EGQMERSQNWGHPGVRQETG DEPKGEKEKKEEEKEQEEEE DPYTFAEIDDSEYDMILANL SIKKKTGSRSFIINRPPAPT PRPTSIPPKEETTPYIAQVF QQKTARRQSDDDKFRGLPKK QDRARIESPAFSTLRGCLTD GQEELILLQEKVKNGKMSMD EALEKFKHWQMGKSGLEMIQ QEKLRQLRDCIIGKRPEEEN VYNKLTIVHHPGGKETAHN |
| Tissue Specificity | Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations. |
| Post Translational Modifications | Phosphorylated on tyrosines upon BCR activation. |
| Function | Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. |
| Protein Name | B-Cell Scaffold Protein With Ankyrin Repeats |
| Alternative Antibody Names | Anti-B-Cell Scaffold Protein With Ankyrin Repeats antibodyAnti-BANK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
