| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BANK1 |
| Gene ID: | 55024 |
| Uniprot ID: | BANK1_HUMAN |
| Immunogen Region: | 516-785 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 516-785 of human BANK1 (NP_060405.4). |
| Immunogen Sequence: | PVANAFQLERPHFTLPGTMV EGQMERSQNWGHPGVRQETG DEPKGEKEKKEEEKEQEEEE DPYTFAEIDDSEYDMILANL SIKKKTGSRSFIINRPPAPT PRPTSIPPKEETTPYIAQVF QQKTARRQSDDDKFRGLPKK QDRARIESPAFSTLRGCLTD GQEELILLQEKVKNGKMSMD EALEKFKHWQMGKSGLEMIQ QEKLRQLRDCIIGKRPEEEN VYNKLTIVHHPGGKETAHN |
| Tissue Specificity | Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations. |
| Post Translational Modifications | Phosphorylated on tyrosines upon BCR activation. |
| Function | Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. |
| Protein Name | B-Cell Scaffold Protein With Ankyrin Repeats |
| Alternative Antibody Names | Anti-B-Cell Scaffold Protein With Ankyrin Repeats antibodyAnti-BANK1 antibody |
Information sourced from Uniprot.org