• Western blot analysis of various lysates using BAALC Rabbit polyclonal antibody (STJ117708) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-BAALC antibody (1-145) (STJ117708)

SKU:
STJ117708

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BAALC (1-145) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BAALC
Gene ID: 79870
Uniprot ID: BAALC_HUMAN
Immunogen Region: 1-145
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human BAALC (NP_079088.1).
Immunogen Sequence: MGCGGSRADAIEPRYYESWT RETESTWLTYTDSDAPPSAA APDSGPEAGGLHSGMLEDGL PSNGVPRSTAPGGIPNPEKK TNCETQCPNPQSLSSGPLTQ KQNGLQTTEAKRDAKRMPAK EVTINVTDSIQQMDRSRRIT KNCVN
Tissue Specificity Predominantly expressed in neuroectoderm-derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells.
Post Translational Modifications Palmitoylation and myristoylation target the protein to the lipid rafts.
Function May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A.
Protein Name Brain And Acute Leukemia Cytoplasmic Protein
Cellular Localisation Cytoplasm
Synapse
Synaptosome
Membrane Raft
Postsynaptic Density
In Neurons
Localizes To Postsynaptic Lipid Rafts
In Myocardial And Skeletal Muscle Cells
Localizes To The Cytoplasm Adjacent To The Inner Cell Membrane
Polarized To One End Of The Myocyte
Alternative Antibody Names Anti-Brain And Acute Leukemia Cytoplasmic Protein antibody
Anti-BAALC antibody

Information sourced from Uniprot.org

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