| Tissue Specificity | Predominantly expressed in neuroectoderm-derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells. |
| Post Translational Modifications | Palmitoylation and myristoylation target the protein to the lipid rafts. |
| Function | May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. |
| Protein Name | Brain And Acute Leukemia Cytoplasmic Protein |
| Cellular Localisation | CytoplasmSynapseSynaptosomeMembrane RaftPostsynaptic DensityIn NeuronsLocalizes To Postsynaptic Lipid RaftsIn Myocardial And Skeletal Muscle CellsLocalizes To The Cytoplasm Adjacent To The Inner Cell MembranePolarized To One End Of The Myocyte |
| Alternative Antibody Names | Anti-Brain And Acute Leukemia Cytoplasmic Protein antibodyAnti-BAALC antibody |
Information sourced from Uniprot.org
