| Function | Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for axon guidance.via its function in O-mannosylation of alpha-dystroglycan (DAG1). |
| Protein Name | Beta-1 -4-Glucuronyltransferase 1I-Beta-1 -3-N-AcetylglucosaminyltransferaseIgntN-Acetyllactosaminide Beta-1 -3-N-AcetylglucosaminyltransferasePoly-N-Acetyllactosamine Extension EnzymeUdp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-5083627Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinLocalizes Near The Trans-Golgi Apparatus |
| Alternative Antibody Names | Anti-Beta-1 -4-Glucuronyltransferase 1 antibodyAnti-I-Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Ignt antibodyAnti-N-Acetyllactosaminide Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Poly-N-Acetyllactosamine Extension Enzyme antibodyAnti-Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 antibodyAnti-B4GAT1 antibodyAnti-B3GNT1 antibodyAnti-B3GNT6 antibody |
Information sourced from Uniprot.org
