| Tissue Specificity | Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus. |
| Function | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer.paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development. |
| Protein Name | Lactosylceramide 1 -3-N-Acetyl-Beta-D-GlucosaminyltransferaseLactotriaosylceramide SynthaseLc(3cer SynthaseLc3 SynthaseUdp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5Bgnt-5Beta-1 -3-Gn-T5Beta-1 -3-N-Acetylglucosaminyltransferase 5Beta3gn-T5 |
| Database Links | Reactome: R-HSA-913709Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 1 -3-N-Acetyl-Beta-D-Glucosaminyltransferase antibodyAnti-Lactotriaosylceramide Synthase antibodyAnti-Lc(3cer Synthase antibodyAnti-Lc3 Synthase antibodyAnti-Udp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Bgnt-5 antibodyAnti-Beta-1 -3-Gn-T5 antibodyAnti-Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Beta3gn-T5 antibodyAnti-B3GNT5 antibody |
Information sourced from Uniprot.org
![Immunohistochemistry analysis of ERK1 in paraffin-embedded mouse heart using [KD Validated] ERK1 Rabbit polyclonal antibody (STJ24487) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/100024/385981/STJ24487_1__03709.1713154955.jpg?c=1 "Immunohistochemistry analysis of ERK1 in paraffin-embedded mouse heart using [KD Validated] ERK1 Rabbit polyclonal antibody (STJ24487) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.")
