Anti-B3GALNT2 antibody (STJA0008094)

SKU:
STJA0008094
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: B3GALNT2
Gene ID: 148789
Uniprot ID: B3GL2_HUMAN
Specificity: This antibody detects endogenous levels of B3GALNT2 at Human, Mouse
Immunogen: Synthesized peptide derived from human B3GALNT2
Post Translational Modifications N-glycosylated.
Function Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
Protein Name Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2
Beta-1 -3-Galnac-T2
Beta-1 -3-N-Acetylgalactosaminyltransferase Ii
Database Links Reactome: R-HSA-5173105
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Endoplasmic Reticulum
Alternative Antibody Names Anti-Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2 antibody
Anti-Beta-1 -3-Galnac-T2 antibody
Anti-Beta-1 -3-N-Acetylgalactosaminyltransferase Ii antibody
Anti-B3GALNT2 antibody

Information sourced from Uniprot.org

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