| Post Translational Modifications | N-glycosylated. |
| Function | Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2Beta-1 -3-Galnac-T2Beta-1 -3-N-Acetylgalactosaminyltransferase Ii |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2 antibodyAnti-Beta-1 -3-Galnac-T2 antibodyAnti-Beta-1 -3-N-Acetylgalactosaminyltransferase Ii antibodyAnti-B3GALNT2 antibody |
Information sourced from Uniprot.org
