Anti-AZIN1 antibody (STJA0006982)

SKU:
STJA0006982
€60.00 - €315.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-antizyme inhibitor 1 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AZIN1
Gene ID: 51582
Uniprot ID: AZIN1_HUMAN
Specificity: This antibody detects endogenous levels of Antizyme inhibitor 1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human Antizyme inhibitor 1
Post Translational Modifications Ubiquitinated, leading to its proteasomal degradation.a process that is reduced in presence of antizyme OAZ1.
Function Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
Protein Name Antizyme Inhibitor 1
Azi
Azi1
Ornithine Decarboxylase Antizyme Inhibitor
Database Links Reactome: R-HSA-350562
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Antizyme Inhibitor 1 antibody
Anti-Azi antibody
Anti-Azi1 antibody
Anti-Ornithine Decarboxylase Antizyme Inhibitor antibody
Anti-AZIN1 antibody
Anti-OAZI antibody
Anti-OAZIN antibody

Information sourced from Uniprot.org

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