| Short Description : | Goat polyclonal antibody anti-ATXN2 (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Applications: | Pep-ELISA/IF/FC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Dog/Cow/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.IF: Strong expression of the protein seen in the cytoplasm of A431 and U2OS cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of A431 cells. Recommended concentration |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ATXN2 |
| Gene ID: | 6311 |
| Uniprot ID: | ATX2_HUMAN |
| Accession Number: | NP_002964.3; NP_001297050.1; NP_001297052.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | SEREGHSINTR |
| Function | Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. |
| Protein Name | Ataxin-2Spinocerebellar Ataxia Type 2 ProteinTrinucleotide Repeat-Containing Gene 13 Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ataxin-2 antibodyAnti-Spinocerebellar Ataxia Type 2 Protein antibodyAnti-Trinucleotide Repeat-Containing Gene 13 Protein antibodyAnti-ATXN2 antibodyAnti-ATX2 antibodyAnti-SCA2 antibodyAnti-TNRC13 antibody |
Information sourced from Uniprot.org
