| Tissue Specificity | Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes. |
| Post Translational Modifications | Heavily glycosylated. |
| Function | Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. |
| Protein Name | AttractinDppt-LMahogany Homolog |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: Secreted |
| Alternative Antibody Names | Anti-Attractin antibodyAnti-Dppt-L antibodyAnti-Mahogany Homolog antibodyAnti-ATRN antibodyAnti-KIAA0548 antibodyAnti-MGCA antibody |
Information sourced from Uniprot.org
