| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ATRN |
| Gene ID: |
8455 |
| Uniprot ID: |
ATRN_HUMAN |
| Immunogen Region: |
84-350 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 84-350 of human ATRN (NP_647538.1). |
| Immunogen Sequence: |
AAAAAAVSGSAAAEAKECDR PCVNGGRCNPGTGQCVCPAG WVGEQCQHCGGRFRLTGSSG FVTDGPGNYKYKTKCTWLIE GQPNRIMRLRFNHFATECSW DHLYVYDGDSIYAPLVAAFS GLIVPERDGNETVPEVVATS GYALLHFFSDAAYNLTGFNI TYSFDMCPNNCSGRGECKIS NSSDTVECECSENWKGEACD IPHCTDNCGFPHRGICNSSD VRGCSCFSDWQGPGCSVPV |
| Tissue Specificity | Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes. |
| Post Translational Modifications | Heavily glycosylated. |
| Function | Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. |
| Protein Name | AttractinDppt-LMahogany Homolog |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: Secreted |
| Alternative Antibody Names | Anti-Attractin antibodyAnti-Dppt-L antibodyAnti-Mahogany Homolog antibodyAnti-ATRN antibodyAnti-KIAA0548 antibodyAnti-MGCA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
