Anti-ATRIP antibody (1-260) (STJ116274)

SKU:
STJ116274
$152.49 - $697.59
Free Shipping
Processing The item has been added

Applications:WB/IF/ICC/IP/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ATRIP
Gene ID:84126
Uniprot ID:ATRIP_HUMAN
Immunogen Region:1-260
Immunogen Sequence:MAGTSAPGSKRRSEPPAPRP GPPPGTGHPPSKRARGFSAA AAPDPDDPFGAHGDFTADDL EELDTLASQALSQCPAAARD VSSDHKVHRLLDGMSKNPSG KNRETVPIKDNFELEVLQAQ YKELKEKMKVMEEEVLIKNG EIKILRDSLHQTESVLEEQR RSHFLLEQEKTQALSDKEKE FSKKLQSLQSELQFKDAEMN ELRTKLQTSERANKLAAPSV SHVSPRKNPSVVIKPEACS
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_569055.1).
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylated by ATR.
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Protein Name Atr-Interacting Protein
Atm And Rad3-Related-Interacting Protein
Database Links Reactome: R-HSA-176187
Reactome: R-HSA-5685938
Reactome: R-HSA-5693607
Reactome: R-HSA-5693616
Reactome: R-HSA-6783310
Reactome: R-HSA-6804756
Reactome: R-HSA-69473
Reactome: R-HSA-9709570
Cellular Localisation Nucleus
Redistributes To Discrete Nuclear Foci Upon Dna Damage
Alternative Antibody Names Anti-Atr-Interacting Protein antibody
Anti-Atm And Rad3-Related-Interacting Protein antibody
Anti-ATRIP antibody
Anti-AGS1 antibody

Information sourced from Uniprot.org