| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP6V1D (1-247) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP6V1D |
| Gene ID: |
51382 |
| Uniprot ID: |
VATD_HUMAN |
| Immunogen Region: |
1-247 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human ATP6V1D (NP_057078.1). |
| Immunogen Sequence: |
MSGKDRIEIFPSRMAQTIMK ARLKGAQTGRNLLKKKSDAL TLRFRQILKKIIETKMLMGE VMREAAFSLAEAKFTAGDFS TTVIQNVNKAQVKIRAKKDN VAGVTLPVFEHYHEGTDSYE LTGLARGGEQLAKLKRNYAK AVELLVELASLQTSFVTLDE AIKITNRRVNAIEHVIIPRI ERTLAYIITELDEREREEFY RLKKIQEKKKILKEKSEKDL EQRRAAGEVLEPANLLAEE |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. |
| Protein Name | V-Type Proton Atpase Subunit DV-Atpase Subunit DV-Atpase 28 Kda Accessory ProteinVacuolar Proton Pump Subunit D |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic VesicleClathrin-Coated Vesicle MembraneCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumLocalizes To Centrosome And The Base Of The Cilium |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit D antibodyAnti-V-Atpase Subunit D antibodyAnti-V-Atpase 28 Kda Accessory Protein antibodyAnti-Vacuolar Proton Pump Subunit D antibodyAnti-ATP6V1D antibodyAnti-ATP6M antibodyAnti-VATD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
