| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP5F1D |
| Gene ID: | 513 |
| Uniprot ID: | ATPD_HUMAN |
| Immunogen Region: | 1-168 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-168 of human ATP5D (NP_001678.1). |
| Immunogen Sequence: | MLPAALLRRPGLGRLVRHAR AYAEAAAAPAAASGPNQMSF TFASPTQVFFNGANVRQVDV PTLTGAFGILAAHVPTLQVL RPGLVVVHAEDGTTSKYFVS SGSIAVNADSSVQLLAEEAV TLDMLDLGAAKANLEKAQAE LVGTADEATRAEIQIRIEAN EALVKALE |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
| Protein Name | Atp Synthase Subunit Delta - Mitochondrial Atp Synthase F1 Subunit Delta F-Atpase Delta Subunit |
| Database Links | Reactome: R-HSA-163210 Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion Mitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Atp Synthase Subunit Delta - Mitochondrial antibody Anti-Atp Synthase F1 Subunit Delta antibody Anti-F-Atpase Delta Subunit antibody Anti-ATP5F1D antibody Anti-ATP5D antibody |
Information sourced from Uniprot.org