Anti-ATP5D antibody (1-168) (STJ111970)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATP5D (1-168) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP5F1D |
| Gene ID | 513 |
| Uniprot ID | ATPD_HUMAN |
| Immunogen Region | 1-168 |
| Immunogen Sequence | MLPAALLRRPGLGRLVRHAR AYAEAAAAPAAASGPNQMSF TFASPTQVFFNGANVRQVDV PTLTGAFGILAAHVPTLQVL RPGLVVVHAEDGTTSKYFVS SGSIAVNADSSVQLLAEEAV TLDMLDLGAAKANLEKAQAE LVGTADEATRAEIQIRIEAN EALVKALE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-168 of human ATP5D (NP_001678.1). |
Additional Info
| Function | Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate. |
| Protein Name | Atp Synthase F(1 Complex Subunit Delta - MitochondrialAtp Synthase F1 Subunit DeltaF-Atpase Delta Subunit |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | MitochondrionMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Atp Synthase F(1 Complex Subunit Delta - Mitochondrial antibodyAnti-Atp Synthase F1 Subunit Delta antibodyAnti-F-Atpase Delta Subunit antibodyAnti-ATP5F1D antibodyAnti-ATP5D antibody |
Information sourced from Uniprot.org