Anti-ATP5B antibody (230-529) [S4MR] (STJ11101294)

Name: Anti-ATP5B antibody (230-529) [S4MR] (STJ11101294)
SKU: STJ11101294
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11101294

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Short Description	Rabbit monoclonal ATPB (230-529) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S4MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:2000-1:20000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ATP5F1B
Gene ID	506
Uniprot ID	ATPB_HUMAN
Immunogen Region	230-529
Immunogen Sequence	YSVFAGVGERTREGNDLYHE MIESGVINLKDATSKVALVY GQMNEPPGARARVALTGLTV AEYFRDQEGQDVLLFIDNIF RFTQAGSEVSALLGRIPSAV GYQPTLATDMGTMQERITTT KKGSITSVQAIYVPADDLTD PAPATTFAHLDATTVLSRAI AELGIYPAVDPLDSTSRIMD PNIVGSEHYDVARGVQKILQ DYKSLQDIIAILGMDELSEE DKLTVSRARKIQRFLSQPF
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 230-529 of human ATPB (NP_001677.2).

Function	Catalytic subunit beta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the subunit alpha (ATP5F1A), forms the catalytic core in the F(1) domain.
Protein Name	Atp Synthase F(1 Complex Subunit Beta - Mitochondrial Atp Synthase F1 Subunit Beta
Database Links	Reactome: R-HSA-1268020 Reactome: R-HSA-163210 Reactome: R-HSA-2151201 Reactome: R-HSA-8949613 Reactome: R-HSA-9837999
Cellular Localisation	Mitochondrion Inner Membrane Peripheral Membrane Protein Matrix Side
Alternative Antibody Names	Anti-Atp Synthase F(1 Complex Subunit Beta - Mitochondrial antibody Anti-Atp Synthase F1 Subunit Beta antibody Anti-ATP5F1B antibody Anti-ATP5B antibody Anti-ATPMB antibody Anti-ATPSB antibody

Information sourced from Uniprot.org