| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP2B4 |
| Gene ID: | 493 |
| Uniprot ID: | AT2B4_HUMAN |
| Immunogen Region: | 1141-1205 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1141-1205 of human ATP2B4 (NP_001675.3). |
| Immunogen Sequence: | ELPRTPLLDEEEEENPDKAS KFGTRVLLLDGEVTPYANTN NNAVDCNQVQLPQSDSSLQS LETSV |
| Tissue Specificity | Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex. |
| Function | Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. By regulating sperm cell calcium homeostasis, may play a role in sperm motility. |
| Protein Name | Plasma Membrane Calcium-Transporting Atpase 4 Pmca4 Matrix-Remodeling-Associated Protein 1 Plasma Membrane Calcium Atpase Isoform 4 Plasma Membrane Calcium Pump Isoform 4 |
| Database Links | Reactome: R-HSA-418359 Reactome: R-HSA-5578775 Reactome: R-HSA-936837 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cell Projection Cilium Flagellum Membrane |
| Alternative Antibody Names | Anti-Plasma Membrane Calcium-Transporting Atpase 4 antibody Anti-Pmca4 antibody Anti-Matrix-Remodeling-Associated Protein 1 antibody Anti-Plasma Membrane Calcium Atpase Isoform 4 antibody Anti-Plasma Membrane Calcium Pump Isoform 4 antibody Anti-ATP2B4 antibody Anti-ATP2B2 antibody Anti-MXRA1 antibody |
Information sourced from Uniprot.org