| Short Description : | Rabbit monoclonal ATP1B3 (180-279) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S3MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP1B3 |
| Gene ID: | 483 |
| Uniprot ID: | AT1B3_HUMAN |
| Immunogen Region: | 180-279 |
| Immunogen Sequence: | GLKPEGVPRIDCVSKNEDIP NVAVYPHNGMIDLKYFPYYG KKLHVGYLQPLVAVQVSFAP NNTGKEVTVECKIDGSANLK SQDDRDKFLGRVMFKITARA |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 180-279 of human ATP1B3 (P54709). |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Beta-3Sodium/Potassium-Dependent Atpase Subunit Beta-3Atpb-3Cd Antigen Cd298 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type Ii Membrane ProteinBasolateral Cell MembraneMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-3 antibodyAnti-Sodium/Potassium-Dependent Atpase Subunit Beta-3 antibodyAnti-Atpb-3 antibodyAnti-Cd Antigen Cd298 antibodyAnti-ATP1B3 antibody |
Information sourced from Uniprot.org
