| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP12A (890-980) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP12A |
| Gene ID: |
479 |
| Uniprot ID: |
AT12A_HUMAN |
| Immunogen Region: |
890-980 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 890-980 of human ATP12A (NP_001172014.1). |
| Immunogen Sequence: |
YFTVYAQEGFLPRTLINLRV EWEKDYVNDLKDSYGQEWTR YQREYLEWTGYTAFFVGILV QQIADLIIRKTRRNSIFQQG LFRNKVIWVGI |
| Tissue Specificity | Expressed in airway epithelial cells (at protein level). Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level). |
| Function | The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon. In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance. |
| Protein Name | Potassium-Transporting Atpase Alpha Chain 2Hk Alpha 2Non-Gastric H(+/K(+ Atpase Subunit AlphaNon-Gastric Na(+/K(+ Atpase Subunit AlphaProton PumpSodium Pump |
| Database Links | Reactome: R-HSA-936837 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium-Transporting Atpase Alpha Chain 2 antibodyAnti-Hk Alpha 2 antibodyAnti-Non-Gastric H(+/K(+ Atpase Subunit Alpha antibodyAnti-Non-Gastric Na(+/K(+ Atpase Subunit Alpha antibodyAnti-Proton Pump antibodyAnti-Sodium Pump antibodyAnti-ATP12A antibodyAnti-ATP1AL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
