Anti-ATP12A antibody (890-980) (STJ116584)

Name: Anti-ATP12A antibody (890-980) (STJ116584)
SKU: STJ116584
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ116584

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Short Description	Rabbit polyclonal ATP12A (890-980) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ATP12A
Gene ID	479
Uniprot ID	AT12A_HUMAN
Immunogen Region	890-980
Immunogen Sequence	YFTVYAQEGFLPRTLINLRV EWEKDYVNDLKDSYGQEWTR YQREYLEWTGYTAFFVGILV QQIADLIIRKTRRNSIFQQG LFRNKVIWVGI
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 890-980 of human ATP12A (NP_001172014.1).

Tissue Specificity	Expressed in airway epithelial cells (at protein level). Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
Function	The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon. In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance.
Protein Name	Potassium-Transporting Atpase Alpha Chain 2 Hk Alpha 2 Non-Gastric H(+/K(+ Atpase Subunit Alpha Non-Gastric Na(+/K(+ Atpase Subunit Alpha Proton Pump Sodium Pump
Database Links	Reactome: R-HSA-936837
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Potassium-Transporting Atpase Alpha Chain 2 antibody Anti-Hk Alpha 2 antibody Anti-Non-Gastric H(+/K(+ Atpase Subunit Alpha antibody Anti-Non-Gastric Na(+/K(+ Atpase Subunit Alpha antibody Anti-Proton Pump antibody Anti-Sodium Pump antibody Anti-ATP12A antibody Anti-ATP1AL1 antibody

Information sourced from Uniprot.org