Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ATMIN (160-360) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATMIN |
Gene ID: |
23300 |
Uniprot ID: |
ATMIN_HUMAN |
Immunogen Region: |
160-360 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2). |
Immunogen Sequence: |
HAEKKHKCSKCSNSYGTEWD LKRHAEDCGKTFRCTCGCPY ASRTALQSHIYRTGHEIPAE HRDPPSKKRKMENCAQNQKL SNKTIESLNNQPIPRPDTQE LEASEIKLEPSFEDSCGSNT DKQTLTTPPRYPQKLLLPKP KVALVKLPVMQFSVMPVFVP TADSSAQPVVLGVDQGSATG AVHLMPLSVGTLILGLDSEA C |
Tissue Specificity | Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle. |
Function | Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription. |
Protein Name | Atm InteractorAtm/Atr-Substrate Chk2-Interacting Zinc Finger ProteinAscizZinc Finger Protein 822 |
Cellular Localisation | NucleusNuclearIn Discrete Foci During G1 Phase |
Alternative Antibody Names | Anti-Atm Interactor antibodyAnti-Atm/Atr-Substrate Chk2-Interacting Zinc Finger Protein antibodyAnti-Asciz antibodyAnti-Zinc Finger Protein 822 antibodyAnti-ATMIN antibodyAnti-KIAA0431 antibodyAnti-ZNF822 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance