| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATL3 |
| Gene ID: |
25923 |
| Uniprot ID: |
ATLA3_HUMAN |
| Immunogen Region: |
360-440 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 360-440 of human ATL3 (NP_056274.3). |
| Immunogen Sequence: |
KDIYYNNMEEVCGGEKPYLS PDILEEKHCEFKQLALDHFK KTKKMGGKDFSFRYQQELEE EIKELYENFCKHNGSKNVFS T |
| Tissue Specificity | Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level). |
| Function | GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. |
| Protein Name | Atlastin-3 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum Tubules And Accumulates In Punctuate Structures Corresponding To 3-Way JunctionsWhich Represent Crossing-Points At Which The Tubules Build A Polygonal Network |
| Alternative Antibody Names | Anti-Atlastin-3 antibodyAnti-ATL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
