| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATL3 |
| Gene ID: | 25923 |
| Uniprot ID: | ATLA3_HUMAN |
| Immunogen Region: | 360-440 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-440 of human ATL3 (NP_056274.3). |
| Immunogen Sequence: | KDIYYNNMEEVCGGEKPYLS PDILEEKHCEFKQLALDHFK KTKKMGGKDFSFRYQQELEE EIKELYENFCKHNGSKNVFS T |
| Tissue Specificity | Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level). |
| Function | GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. |
| Protein Name | Atlastin-3 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum Tubules And Accumulates In Punctuate Structures Corresponding To 3-Way JunctionsWhich Represent Crossing-Points At Which The Tubules Build A Polygonal Network |
| Alternative Antibody Names | Anti-Atlastin-3 antibodyAnti-ATL3 antibody |
Information sourced from Uniprot.org