Anti-ATF3 antibody [R05-2E0] (STJA0035122)

SKU:
STJA0035122
€166.88 - €351.88
Processing The item has been added

Host: Rabbit
Applications: WB/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-ATF3 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R05-2E0
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: ATF3
Gene ID: 467
Uniprot ID: ATF3_HUMAN
Immunogen: Recombinant protein of human ATF3
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Isoform 3: Stress-induced isoform, counteracts the transcriptional repression of isoform 1.
Protein Name Cyclic Amp-Dependent Transcription Factor Atf-3
Camp-Dependent Transcription Factor Atf-3
Activating Transcription Factor 3
Database Links Reactome: R-HSA-380994
Reactome: R-HSA-9633012
Reactome: R-HSA-9648895
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclic Amp-Dependent Transcription Factor Atf-3 antibody
Anti-Camp-Dependent Transcription Factor Atf-3 antibody
Anti-Activating Transcription Factor 3 antibody
Anti-ATF3 antibody

Information sourced from Uniprot.org