| Host: | Mouse |
| Applications: | IHC-F/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Ataxin-2 binding protein 1 for use in IHC-F and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 1G10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Purification: | IgG |
| Dilution Range: | WB 1:1000-1:2000ICC 1:500-1:1000 |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for |
| Gene Symbol: | RBFOX1 |
| Gene ID: | 54715 |
| Uniprot ID: | RFOX1_HUMAN |
| Specificity: | The antibody reacts with a 48 kDa and 46 kDa band by Western blot on extract from mouse brain. It has also been used successfully for immunocytochemistry on rat neuronal cultures. |
| Immunogen: | N-terminal 100 amino acids of human Fox1 as expressed in and purified from E. coli. |
| Immunogen Sequence: | Human |
| Tissue Specificity | Predominantly expressed in muscle and brain. |
| Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. |
| Protein Name | Rna Binding Protein Fox-1 Homolog 1Ataxin-2-Binding Protein 1Fox-1 Homolog AHexaribonucleotide-Binding Protein 1 |
| Database Links | Reactome: R-HSA-9022707 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 1 antibodyAnti-Ataxin-2-Binding Protein 1 antibodyAnti-Fox-1 Homolog A antibodyAnti-Hexaribonucleotide-Binding Protein 1 antibodyAnti-RBFOX1 antibodyAnti-A2BP antibodyAnti-A2BP1 antibodyAnti-FOX1 antibodyAnti-HRNBP1 antibody |
Information sourced from Uniprot.org