Anti-Ataxin-2 binding protein 1 antibody [1G10] (STJA0040778)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenN-terminal 100 amino acids of human Fox1 as expressed in and purified from E. coli.
General Information
| Short Description | Mouse monoclonal anti-Ataxin-2 binding protein 1 for use in IHC-F and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1G10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | IgG |
| Dilution Range | WB 1:1000-1:2000ICC 1:500-1:1000 |
| Formulation | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for |
Target Information
| Gene Symbol | RBFOX1 |
| Gene ID | 54715 |
| Uniprot ID | RFOX1_HUMAN |
| Immunogen | N-terminal 100 amino acids of human Fox1 as expressed in and purified from E. coli. |
| Immunogen Sequence | Human |
| Specificity | The antibody reacts with a 48 kDa and 46 kDa band by Western blot on extract from mouse brain. It has also been used successfully for immunocytochemistry on rat neuronal cultures. |
Additional Info
| Tissue Specificity | Predominantly expressed in muscle and brain. |
| Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. |
| Protein Name | Rna Binding Protein Fox-1 Homolog 1Ataxin-2-Binding Protein 1Fox-1 Homolog AHexaribonucleotide-Binding Protein 1 |
| Database Links | Reactome: R-HSA-9022707 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 1 antibodyAnti-Ataxin-2-Binding Protein 1 antibodyAnti-Fox-1 Homolog A antibodyAnti-Hexaribonucleotide-Binding Protein 1 antibodyAnti-RBFOX1 antibodyAnti-A2BP antibodyAnti-A2BP1 antibodyAnti-FOX1 antibodyAnti-HRNBP1 antibody |
Information sourced from Uniprot.org