Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ATAD3A/ATAD3B (1-240) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunogen Region: |
1-240 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ATAD3B (NP_114127.3). |
Immunogen Sequence: |
MSWLFGVNKGPKGEGAGPPP PLPPAQPGAEGGGDRGLGDR PAPKDKWSNFDPTGLERAAK AARELEHSRYAKEALNLAQM QEQTLQLEQQSKLKEYEAAV EQLKSEQIRAQAEERRKTLS EETRQHQARAQYQDKLARQR YEDQLKQQQLLNEENLRKQE ESVQKQEAMRRATVEREMEL RHKNEMLRVETEARARAKAE RENADIIREQIRLKASEHRQ TVLESIRTAGTLFGEGFRA |
Background | The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance