| Short Description : | Rabbit polyclonal anti-ATPase family AAA domain-containing protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATAD2 |
| Gene ID: | 29028 |
| Uniprot ID: | ATAD2_HUMAN |
| Immunogen: | Synthesized peptide derived from human ATAD2 |
| Specificity: | This antibody detects endogenous levels of ATAD2 at Human, Mouse |
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
| Protein Name | Atpase Family Aaa Domain-Containing Protein 2Aaa Nuclear Coregulator Cancer-Associated ProteinAncca |
| Database Links | Reactome: R-HSA-8866910 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Atpase Family Aaa Domain-Containing Protein 2 antibodyAnti-Aaa Nuclear Coregulator Cancer-Associated Protein antibodyAnti-Ancca antibodyAnti-ATAD2 antibodyAnti-L16 antibodyAnti-PRO2000 antibody |
Information sourced from Uniprot.org
