| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASPA |
| Gene ID: | 443 |
| Uniprot ID: | ACY2_HUMAN |
| Immunogen Region: | 1-313 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human ASPA (NP_001121557.1). |
| Immunogen Sequence: | MTSCHIAEEHIQKVAIFGGT HGNELTGVFLVKHWLENGAE IQRTGLEVKPFITNPRAVKK CTRYIDCDLNRIFDLENLGK KMSEDLPYEVRRAQEINHLF GPKDSEDSYDIIFDLHNTTS NMGCTLILEDSRNNFLIQMF HYIKTSLAPLPCYVYLIEHP SLKYATTRSIAKYPVGIEVG PQPQGVLRADILDQMRKMIK HALDFIHHFNEGKEFPPCAI EVYKIIEKVDYPRDENGEI |
| Tissue Specificity | Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver. |
| Function | Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids. |
| Protein Name | AspartoacylaseAminoacylase-2Acy-2 |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Aspartoacylase antibodyAnti-Aminoacylase-2 antibodyAnti-Acy-2 antibodyAnti-ASPA antibodyAnti-ACY2 antibodyAnti-ASP antibody |
Information sourced from Uniprot.org