| Short Description : | Rabbit polyclonal ASMT (76-298) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASMT |
| Gene ID: | 438 |
| Uniprot ID: | ASMT_HUMAN |
| Immunogen Region: | 76-298 |
| Immunogen Sequence: | ETRGGKAFYRNTELSSDYLT TVSPTSQCSMLKYMGRTSYR CWGHLADAVREGRNQYLETF GVPAEELFTAIYRSEGERLQ FMQALQEVWSVNGRSVLTAF DLSVFPLMCDLGGDFFKDPL PEADLYILARVLHDWADGKC SHLLERIYHTCKPGGGILVI ESLLDEDRRGPLLTQLYSLN MLVQTEGQERTPTHYHMLLS SAGFRDFQFKKTGAIYDAIL ARK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-298 of human ASMT (NP_001164510.1). |
| Tissue Specificity | Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level, and not at the protein level. |
| Function | Isoform 1: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2: Does not show Acetylserotonin O-methyltransferase activity. Isoform 3: Does not show Acetylserotonin O-methyltransferase activity. |
| Protein Name | Acetylserotonin O-MethyltransferaseHydroxyindole O-MethyltransferaseHiomt |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Acetylserotonin O-Methyltransferase antibodyAnti-Hydroxyindole O-Methyltransferase antibodyAnti-Hiomt antibodyAnti-ASMT antibody |
Information sourced from Uniprot.org
![Immunohistochemistry analysis of CDK2 in paraffin-embedded human esophageal cancer using [KO Validated] CDK2 Rabbit polyclonal antibody (STJ113540) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/92940/373680/STJ113540_1__78661.1713139974.jpg?c=1 "Immunohistochemistry analysis of CDK2 in paraffin-embedded human esophageal cancer using [KO Validated] CDK2 Rabbit polyclonal antibody (STJ113540) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.")
