| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Histone chaperone ASF1B (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ASF1B |
| Gene ID: |
55723 |
| Uniprot ID: |
ASF1B_HUMAN |
| Immunogen Region: |
101-150 aa |
| Specificity: |
ASF1B Polyclonal Antibody detects endogenous levels of ASF1B protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ASF1B at the amino acid range 101-150 |
| Post Translational Modifications | Phosphorylated by TLK1 and TLK2. |
| Function | Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development. |
| Protein Name | Histone Chaperone Asf1bAnti-Silencing Function Protein 1 Homolog BHasf1Hasf1bCcg1-Interacting Factor A-IiCia-IiHcia-Ii |
| Cellular Localisation | NucleusCytoplasmCytosol |
| Alternative Antibody Names | Anti-Histone Chaperone Asf1b antibodyAnti-Anti-Silencing Function Protein 1 Homolog B antibodyAnti-Hasf1 antibodyAnti-Hasf1b antibodyAnti-Ccg1-Interacting Factor A-Ii antibodyAnti-Cia-Ii antibodyAnti-Hcia-Ii antibodyAnti-ASF1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
