| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARVCF |
| Gene ID: | 421 |
| Uniprot ID: | ARVC_HUMAN |
| Immunogen Region: | 1-100 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARVCF (NP_001661.1). |
| Immunogen Sequence: | MEDCNVHSAASILASVKEQE ARFERLTRALEQERRHVALQ LERAQQPGMVSGGMGSGQPL PMAWQQLVLQEQSPGSQASL ATMPEAPDVLEETVTVEEDP |
| Tissue Specificity | Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung. Expressed in dermal connective tissue, salivary gland duct and in the corneal layer (at protein level). Expressed in arrector pili muscle (at protein level). High levels detected in epithelial cells with lower levels found in fibroblasts and T lymphocytes. |
| Function | Contributes to the regulation of alternative splicing of pre-mRNAs. |
| Protein Name | Splicing Regulator ArvcfArmadillo Repeat Protein Deleted In Velo-Cardio-Facial Syndrome |
| Database Links | |
| Cellular Localisation | Cell JunctionAdherens JunctionNucleusCytoplasmIn HeartLocalizes At Area CompositaThe Mixed-Type Junctional Structure Composed Of Both Desmosomal And Adherens Junctional Proteins |
| Alternative Antibody Names | Anti-Splicing Regulator Arvcf antibodyAnti-Armadillo Repeat Protein Deleted In Velo-Cardio-Facial Syndrome antibodyAnti-ARVCF antibody |
Information sourced from Uniprot.org
