| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ARHGDIG (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 25kDa band observed in lysates of cell line HeLa (calculated MW of 25.1kDa according to NP_001167.2). Recommended concentration: 0.5-2µg/ml. Primary incubation was 1 hour.I |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ARHGDIG |
| Gene ID: | 398 |
| Uniprot ID: | GDIR3_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_001167.2 |
| Immunogen Sequence: | EAVPEYRAPGRK |
| Function | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. |
| Protein Name | Rho Gdp-Dissociation Inhibitor 3Rho Gdi 3Rho-Gdi Gamma |
| Database Links | Reactome: R-HSA-9013026Reactome: R-HSA-9013148Reactome: R-HSA-9013407Reactome: R-HSA-9013408 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Rho Gdp-Dissociation Inhibitor 3 antibodyAnti-Rho Gdi 3 antibodyAnti-Rho-Gdi Gamma antibodyAnti-ARHGDIG antibody |
Information sourced from Uniprot.org
