| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-APOBEC2 (12-26) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 26kDa band observed in Human Heart and Skeletal Muscle lysates (calculated MW of 25.7kDa according to NP_006780.1). Recommended concentration: 1-3µg/ml.An additional band of 90kD |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | APOBEC2 |
| Gene ID: | 10930 |
| Uniprot ID: | ABEC2_HUMAN |
| Immunogen Region: | 12-26 |
| Accession Number: | NP_006780.1 |
| Immunogen Sequence: | EAASQNGEDLENLDD |
| Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-2Mrna(Cytosine(6666 Deaminase 2 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-2 antibodyAnti-Mrna(Cytosine(6666 Deaminase 2 antibodyAnti-APOBEC2 antibody |
Information sourced from Uniprot.org
