| Short Description : | Rabbit polyclonal APOBEC2 (1-224) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOBEC2 |
| Gene ID: | 10930 |
| Uniprot ID: | ABEC2_HUMAN |
| Immunogen Region: | 1-224 |
| Immunogen Sequence: | MAQKEEAAVATEAASQNGED LENLDDPEKLKELIELPPFE IVTGERLPANFFKFQFRNVE YSSGRNKTFLCYVVEAQGKG GQVQASRGYLEDEHAAAHAE EAFFNTILPAFDPALRYNVT WYVSSSPCAACADRIIKTLS KTKNLRLLILVGRLFMWEEP EIQAALKKLKEAGCKLRIMK PQDFEYVWQNFVEQEEGESK AFQPWEDIQENFLYYEEKLA DILK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1). |
| Tissue Specificity | Expressed exclusively in heart and skeletal muscle. |
| Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-2Mrna(Cytosine(6666 Deaminase 2 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-2 antibodyAnti-Mrna(Cytosine(6666 Deaminase 2 antibodyAnti-APOBEC2 antibody |
Information sourced from Uniprot.org
