| Post Translational Modifications | Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation. |
| Function | Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. |
| Protein Name | Nad(Ph-Hydrate EpimeraseApolipoprotein A-I-Binding ProteinAi-BpNad(Phx EpimeraseNaxeYjef N-Terminal Domain-Containing Protein 1Yjef_n1 |
| Database Links | Reactome: R-HSA-197264 |
| Cellular Localisation | MitochondrionSecretedIn SpermSecretion Gradually Increases During Capacitation |
| Alternative Antibody Names | Anti-Nad(Ph-Hydrate Epimerase antibodyAnti-Apolipoprotein A-I-Binding Protein antibodyAnti-Ai-Bp antibodyAnti-Nad(Phx Epimerase antibodyAnti-Naxe antibodyAnti-Yjef N-Terminal Domain-Containing Protein 1 antibodyAnti-Yjef_n1 antibodyAnti-NAXE antibodyAnti-AIBP antibodyAnti-APOA1BP antibodyAnti-YJEFN1 antibody |
Information sourced from Uniprot.org
